NOVEL CAS9 PROTEINS AND GUIDING FEATURES FOR DNA TARGETING AND GENOME EDITING

The present invention is directed to methods and compositions comprising novel CRISPR polypeptides and polynucleotides for site-specific cleavage and nicking of nucleic acids, transcriptional control and genome editing. La présente invention concerne des méthodes et des compositions comprenant de no...

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Hauptverfasser:	BRINER, ALEXANDRA E, BARRANGOU, RODOLPHE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention is directed to methods and compositions comprising novel CRISPR polypeptides and polynucleotides for site-specific cleavage and nicking of nucleic acids, transcriptional control and genome editing. La présente invention concerne des méthodes et des compositions comprenant de nouveaux polypeptides et polynucléotides CRISPR pour le clivage spécifique de site et la coupure d'acides nucléiques, et le contrôle de la transcription et l'édition du génome.