PERILLIC ACID DERIVATIVE, METHOD FOR PREPARING A PERILLIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION, USE OF A PERILLIC ACID DERIVATIVE AND CANCER TREATMENT METHOD

The present invention provides a perillic acid derivative in the form of a salt having formula II, with anti-cancer activity, in which the counter-ion M+ comprises alkali or alkaline earth metals, such as Na+ (sodium), K+ (potassium), Ca+2/2 (calcium), etc. The invention further relates to a method...

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Hauptverfasser: TAPPIN, MARCELO RAUL ROMERO, SAMPAIO, ANDRÉ LUIZ FRANCO, DE LACERDA, PAULO SÉRGIO BERGO, LÓPEZ, RAQUEL ELISA DA SILVA, SIANI, ANTONIO CARLOS, BON, ELBA PINTO DA SILVA, FERRARA, MARIA ANTONIETA
Format: Patent
Sprache:eng ; fre ; por
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Zusammenfassung:The present invention provides a perillic acid derivative in the form of a salt having formula II, with anti-cancer activity, in which the counter-ion M+ comprises alkali or alkaline earth metals, such as Na+ (sodium), K+ (potassium), Ca+2/2 (calcium), etc. The invention further relates to a method for producing the compound, a pharmaceutical composition, the use of the compound and a cancer treatment method. La présente invention concerne un composé de l'acide pérylique sous forme de sel présentant la formule II, possédant une activité anticancéreuse, le contre-ion M+ comprenant des métaux alcalins ou alcalino-terreux, tels que Na+ (sodium), K+ (potassium), Ca+2/2 (calcium), etc. L'invention concerne en outre un procédé d'obtention du composé, une composition pharmaceutique, l'utilisation de cette composition et une méthode de traitement du cancer. A presente invenção proporciona um composto do ácido perílíco em forma de sal possuindo a Fórmula lI, tendo a atividade anti-câncer, onde o contra-íon M* compreende metais alcalinos ou alcalinos terrosos, como Na* (sódio), K+ (potássio), Ca+2/2 (cálcio), etc. A invenção contempla ainda um processo de obtenção do composto, uma composição farmacêutica, uso do composto e um método de tratamento de câncer.