IMPROVED PROCESS FOR PREPARATION OF AMORPHOUS LINACLOTIDE

IMPROVED PROCESS FOR PREPARATION OF AMORPHOUS LINACLOTIDE

The present application relates to an improved process for the formation of disulfide bonds in linaclotide. The present application also relates to an improved process for the purification of linaclotide. La présente invention concerne un procédé amélioré pour la formation de liaisons disulfure dans...

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Hauptverfasser: KASINA, VARA PRASAD, TIRUMALAREDDY, RAMREDDY, KALITA, DIPAK, NALAMOTHU, SIVANNARAYANA, KHAN, RASHID ABDUL REHMAN, DESHMUKH, SHIVSHANKAR, VUTUKURU, NAGA CHANDRA SEKHAR, BALAKUMARAN, KESAVAN, VILVA, MOHAN SUNDARAM, MUSTOORI, SAIRAM, NIVRUTTI, RAMRAO JOGDAND
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present application relates to an improved process for the formation of disulfide bonds in linaclotide. The present application also relates to an improved process for the purification of linaclotide. La présente invention concerne un procédé amélioré pour la formation de liaisons disulfure dans le linaclotide. La présente invention concerne un procédé amélioré pour la purification du linaclotide.