NANOPARTICLE FORMULATIONS OF LOW-WATER SOLUBILITY ACTIVES

NANOPARTICLE FORMULATIONS OF LOW-WATER SOLUBILITY ACTIVES

Disclosed are compositions including nanoparticles comprising a poorly aqueous soluble polymer, an ionizable active agent, and a counterion having an opposite charge as the ionizable active agent, as well as methods of making and using the compositions. L'invention concerne des compositions con...

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Bibliographische Detailangaben
Hauptverfasser: MORGEN, MICHAEL MARK, MILLER, WARREN KENYON
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Disclosed are compositions including nanoparticles comprising a poorly aqueous soluble polymer, an ionizable active agent, and a counterion having an opposite charge as the ionizable active agent, as well as methods of making and using the compositions. L'invention concerne des compositions contenant des nanoparticules comprenant un polymère très peu soluble dans l'eau, un agent actif ionisable, et un contre-ion ayant une charge opposée tel que l'agent actif ionisable, ainsi que des procédés de fabrication et d'utilisation de ces compositions.