METHODS OF ANALYZING NUCLEIC ACIDS FROM INDIVIDUAL CELLS OR CELL POPULATIONS

Methods, compositions and systems for analyzing individual cells or cell populations through the partitioned analysis of contents of individual cells or cell populations. Individual cells or cell populations are co-partitioned with processing reagents for accessing cellular contents, and for uniquel...

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Hauptverfasser:	HINDSON, CHRISTOPHER, MARTIN, JAROSZ, MIRNA, ZHENG, GRACE, X.Y, SCHNALL-LEVIN, MICHAEL, HARDENBOL, PAUL, NESS, KEVIN, DEAN, BELGRADER, PHILIP, SAXONOV, SERGE, HINDSON, BENJAMIN, J, BHARADWAJ, RAJIV
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Methods, compositions and systems for analyzing individual cells or cell populations through the partitioned analysis of contents of individual cells or cell populations. Individual cells or cell populations are co-partitioned with processing reagents for accessing cellular contents, and for uniquely identifying the contents of a given cell or cell population, and subsequently analyzing the cell's contents and characterizing it as having derived from an individual cell or cell population, including analysis and characterization of the cell's nucleic acids through sequencing. L'invention concerne des procédés, des compositions et des systèmes permettant d'analyser des cellules individuelles ou des populations cellulaires par l'analyse séparée du contenu de cellules individuelles ou de populations cellulaires. Des cellules individuelles ou des populations de cellules sont co-séparées avec des réactifs de traitement pour accéder aux contenus cellulaires, et pour identifier de manière unique le contenu d'une cellule ou d'une population de cellules donnée, et analyser ensuite le contenu de la cellule et le caractériser comme ayant dérivé d'une cellule individuelle ou d'une population de cellules, notamment par analyse et caractérisation des acides nucléiques de la cellule par séquençage.