SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF PAIN

The present application relates to a series of substituted imidazo[l,2-a]pyridine compounds of formula (I), pharmaceutically acceptable salts, pharmaceutically acceptable solvates or stereoisomers thereof, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of mak...

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Bibliographische Detailangaben
Hauptverfasser:	PARADKAR, VIDYADHAR, SASMAL, PRADIP, KUMAR, TEHIM, ASHOK, AHMED, SHAHADAT
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present application relates to a series of substituted imidazo[l,2-a]pyridine compounds of formula (I), pharmaceutically acceptable salts, pharmaceutically acceptable solvates or stereoisomers thereof, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds. La présente invention concerne une série de composés imidazo[1,2-a]pyridines substitués de formule (I), leurs sels pharmaceutiquement acceptables, leurs stéréoisomères ou solvates pharmaceutiquement acceptables, leur utilisation en tant qu'inhibiteurs de la famille de la protéine kinase du récepteur kinase lié à la tropomyosine (Trk), un procédé de fabrication et des compositions pharmaceutiques comprenant de tels composés.