PRODUCTS FOR REPAIRING CARTILAGE LESIONS, METHOD OF PREPARATION AND USES THEREOF

Products for repairing cartilage lesions, method of preparation and uses thereof The present disclosure provides products and methods of preparation thereof, said products comprising a matrix of methacrylated gellan gum having a methacrylation degree between 1.5 and 6 %, cartilage forming cells and...

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Hauptverfasser: VILELA GOMES, CARLOS ALBERTO, FREIRE GERTRUDES, ANA CATARINA, ROMERO AMANDI DE SOUSA, RUI PEDRO, XAVIER CARLOS DOS SANTOS, TÍRCIA SUSETE, DA SILVA MORAIS, ALAIN JOSÉ, GONÇALVES DOS REIS, RUI LUÍS, CORREIA, CRISTINA, ANTUNES CORREIA DE OLIVEIRA, JOAQUIM MIGUEL, DUARTE COELHO DO SAMEIRO ESPREGUEIRA MENDES, JOÃODUARTE
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Sprache:eng ; fre
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Zusammenfassung:Products for repairing cartilage lesions, method of preparation and uses thereof The present disclosure provides products and methods of preparation thereof, said products comprising a matrix of methacrylated gellan gum having a methacrylation degree between 1.5 and 6 %, cartilage forming cells and a physiologically acceptable ionic solution containing cations, for application in tissue engineering and regenerative medicine, in particular cartilage lesions. La présente invention concerne des produits et des procédés de préparation associés, lesdits produits comprenant une matrice de gomme gellane méthacrylée ayant un degré methacrylation entre 1,5 et 6 %, des cellules formant le cartilage et une solution ionique contenant des cations physiologiquement acceptable, pour une application en génie tissulaire et en médecine régénérative, en particulier pour les lésions du cartilage.