3-OXO-TETRAHYDRO-FURO[3,2-B]PYRROL-4(5H)-YL) DERIVATIVES I

3-OXO-TETRAHYDRO-FURO[3,2-B]PYRROL-4(5H)-YL) DERIVATIVES I

The invention relates to amidic oxotetrahydro-2H-furo[3.2-b]pyrrol-4(5H)-yl) derivatives as dual CatS/K inhibitors, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders. L'...

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Bibliographische Detailangaben
Hauptverfasser: KIME, ROBERT, STEINHAGEN, HENNING, RATCLIFFE, PAUL, HERTRAMPF, THORSTEN, NARDI, ANTONIO, CRAAN, TOBIAS, LESCH, BERNHARD
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to amidic oxotetrahydro-2H-furo[3.2-b]pyrrol-4(5H)-yl) derivatives as dual CatS/K inhibitors, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders. L'invention concerne des dérivés amide oxotétrahydro-2H-furo[3.2-b]pyrrol-4(5H)-yl) utiles en tant qu'inhibiteurs doubles CatS/K, des compositions pharmaceutiques contenant ces composés et également ces composés à utiliser dans le traitement et/ou la prophylaxie de la douleur et d'autres maladies et/ou troubles.