BIOSYNTHETIC POLYPEPTIDE AND METHODS OF USE

The present disclosure provides for a polypeptide scaffold capable of identifying and developing polyketide synthase enzymes. Moreover, the polypeptide of the present disclosure is utilized in methods for screening to verify the activity and functionality of identified polyketide synthase enzymes. I...

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Hauptverfasser: WONG, FONG TIAN, HOON, SHAWN, HO, YING SWAN, ZHANG, MINGZI
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creator WONG, FONG TIAN
HOON, SHAWN
HO, YING SWAN
ZHANG, MINGZI
description The present disclosure provides for a polypeptide scaffold capable of identifying and developing polyketide synthase enzymes. Moreover, the polypeptide of the present disclosure is utilized in methods for screening to verify the activity and functionality of identified polyketide synthase enzymes. In addition, the polypeptide of the present disclosure is utilized in a method for producing polyketides from Acyl-Coenzyme A derivatives. La présente invention concerne un échafaudage polypeptidique permettant d'identifier et de développer des enzymes polycétide synthases. De plus, le polypeptide selon la présente invention est utilisé dans des procédés de criblage pour vérifier l'activité et la fonctionnalité d'enzymes polycétide synthases identifiées. De plus, le polypeptide selon la présente invention est utilisé dans un procédé de production de polycétides à partir de dérivés d'Acyl-coenzyme A.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title BIOSYNTHETIC POLYPEPTIDE AND METHODS OF USE
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