BIOSYNTHETIC POLYPEPTIDE AND METHODS OF USE

The present disclosure provides for a polypeptide scaffold capable of identifying and developing polyketide synthase enzymes. Moreover, the polypeptide of the present disclosure is utilized in methods for screening to verify the activity and functionality of identified polyketide synthase enzymes. I...

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Bibliographische Detailangaben
Hauptverfasser:	WONG, FONG TIAN, HOON, SHAWN, HO, YING SWAN, ZHANG, MINGZI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure provides for a polypeptide scaffold capable of identifying and developing polyketide synthase enzymes. Moreover, the polypeptide of the present disclosure is utilized in methods for screening to verify the activity and functionality of identified polyketide synthase enzymes. In addition, the polypeptide of the present disclosure is utilized in a method for producing polyketides from Acyl-Coenzyme A derivatives. La présente invention concerne un échafaudage polypeptidique permettant d'identifier et de développer des enzymes polycétide synthases. De plus, le polypeptide selon la présente invention est utilisé dans des procédés de criblage pour vérifier l'activité et la fonctionnalité d'enzymes polycétide synthases identifiées. De plus, le polypeptide selon la présente invention est utilisé dans un procédé de production de polycétides à partir de dérivés d'Acyl-coenzyme A.