METHOD FOR SCREENING TRP CHANNELS

Compounds and methods for modifying sensory perception associated with transient sensory receptors TRPA1, TRPV1, and TRPA1V1. A method for screening compounds for modulation of TRPA1, TRPV1, and/or TRPA1V1. Compositions comprising TRPA1V1 agonists or antagonists, for modifying sensory perception of...

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Bibliographische Detailangaben
Hauptverfasser:	SREEKRISHNA, KOTI, TATACHAR, LIN, YAKANG
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	Compounds and methods for modifying sensory perception associated with transient sensory receptors TRPA1, TRPV1, and TRPA1V1. A method for screening compounds for modulation of TRPA1, TRPV1, and/or TRPA1V1. Compositions comprising TRPA1V1 agonists or antagonists, for modifying sensory perception of the compositions. L'invention concerne des composés et des méthodes de modification de la perception sensorielle associée aux récepteurs sensoriels transitoires TRPA1, TRPV1 et TRPA1V1. L'invention concerne également une méthode de criblage de composés pour la modulation de TRPA1, TRPV1 et/ou TRPA1V1. Elle se rapporte en outre à des compositions comprenant des agonistes ou des antagonistes de TRPA1V1, pour modifier la perception sensorielle des compositions.