PHARMACEUTICAL COMPOSITIONS AND SALTS OF A 1,2,4-OXADIAZOLE BENZOIC ACID

Provided herein are pharmaceutical compositions, which comprise a 1,2,4-oxadiazole benzoic acid or a pharmaceutically acceptable salt thereof. Further provided herein are certain pharmaceutically acceptable salts of a 1,2,4-oxadiazole benzoic acid and methods for making the same. Further provided he...

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Bibliographische Detailangaben
Hauptverfasser:	TAKASUGI, JAMES, DALI, MANDAR, V, WELCH, ELLEN, WEETALL, MARLA, L
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES FISHING FORESTRY HUMAN NECESSITIES HUNTING PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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Beschreibung
Zusammenfassung:	Provided herein are pharmaceutical compositions, which comprise a 1,2,4-oxadiazole benzoic acid or a pharmaceutically acceptable salt thereof. Further provided herein are certain pharmaceutically acceptable salts of a 1,2,4-oxadiazole benzoic acid and methods for making the same. Further provided herein are methods of treating or preventing a disease associated with a nonsense mutation or a premature stop codon, comprising administering such pharmaceutical compositions or pharmaceutically acceptable salts to a patient having a disease associated with a nonsense mutation or a premature stop codon. L'invention concerne des compositions pharmaceutiques, qui comprennent un acide benzoïque 1,2,4-oxadiazole ou un sel pharmaceutiquement acceptable de ce dernier. L'invention concerne en outre certains sels pharmaceutiquement acceptables d'un acide benzoïque 1,2,4-oxadiazole, et leurs procédés de fabrication. L'invention concerne en outre des procédés pour traiter ou prévenir une maladie associée à une mutation non-sens ou un codon d'arrêt prématuré, comprenant l'administration de telles compositions pharmaceutiques ou de tels sels pharmaceutiquement acceptables à un patient ayant une maladie associée à une mutation non-sens ou un codon d'arrêt prématuré.