LABELED MOLECULAR AGENTS FOR IMAGING CYSTINE/GLUTAMATE ANTI PORTER

LABELED MOLECULAR AGENTS FOR IMAGING CYSTINE/GLUTAMATE ANTI PORTER

Imaging agents are described that comprise labeled substrates capable of being introduced into cells via the cystine/glutamate antiporter. The substrates may be used for imaging or detecting oxidative stress in cells by introducing the labeled agents into cells via the cystine/glutamate antiporter a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HAY, BRUCE, ALLAN, WEBSTER, JACK, MATHEW
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Imaging agents are described that comprise labeled substrates capable of being introduced into cells via the cystine/glutamate antiporter. The substrates may be used for imaging or detecting oxidative stress in cells by introducing the labeled agents into cells via the cystine/glutamate antiporter and subsequent detection. L'invention concerne des agents d'imagerie qui comprennent des substrats marqués pouvant être introduits dans des cellules via l'antiport cystine/glutamate. Les substrats peuvent être utilisés pour l'imagerie ou la détection du stress oxydatif dans des cellules par l'introduction des agents marqués dans des cellules via l'antiport cystine/glutamate et la détection consécutive.