MEANS AND METHODS FOR DETECTING ACTIVATED MALT1

The present invention provides means and methods for selectively detecting activated MALT1 in a sample. Moreover, the present invention provides a method for diagnosing diseases, which are characterized by an increased MALT1 activity. Finally, the present invention provides methods for identifying p...

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Bibliographische Detailangaben
Hauptverfasser:	EITELHUBER, ANDREA, KRAPPMANN, DANIEL, VERHEIST, STEVEN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides means and methods for selectively detecting activated MALT1 in a sample. Moreover, the present invention provides a method for diagnosing diseases, which are characterized by an increased MALT1 activity. Finally, the present invention provides methods for identifying patients which are amenable to treatment with a therapeutic agent capable of inhibiting MALT1 activity. La présente invention concerne des moyens et des procédés de détection sélective de MALT1 activé dans un échantillon. En outre, la présente invention concerne un procédé de diagnostic de maladies, qui sont caractérisées par une activité de MALT1 accrue. Enfin, la présente invention concerne des procédés d'identification de patients qui sont susceptibles de suivre un traitement à l'aide d'un agent thérapeutique pouvant inhiber l'activité de MALT1.