CRYSTALLINE FORMS OF TAPENTADOL INTERMEDIATE
The present invention pertains to a crystalline and stable form of (βR,γR)-γ-ethyl-N,N,β-trimethyl-3-(phenylmethoxy)benzenepropanamine, as well as to processes for its preparation, and its use in the preparation of tapentadol and pharmaceutically acceptable salts thereof. La présente invention conce...
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| Format: | Patent |
| Sprache: | eng ; fre |
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| Zusammenfassung: | The present invention pertains to a crystalline and stable form of (βR,γR)-γ-ethyl-N,N,β-trimethyl-3-(phenylmethoxy)benzenepropanamine, as well as to processes for its preparation, and its use in the preparation of tapentadol and pharmaceutically acceptable salts thereof.
La présente invention concerne une forme cristalline et stable de (βR,γR)-γ-éthyl-N,N,β-triméthyl-3-(phénylméthoxy)benzènepropanamine, ainsi que des procédés de préparation et ses utilisations dans la préparation de tapentadol et de sels de qualité pharmaceutique de celui-ci. |
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