FUNCTIONALIZED FURAN-2-SULFONAMIDES EXHIBITING ENDOTHELIAL LIPASE INHIBITION

The present invention relates to pharmaceutical compositions comprising furan-2-sulfonamide derivatives. The present invention further relates to methods of treatment of diseases or conditions associated with endothelial lipase activity, including coronary artery disease and low HDL-C. La présente i...

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Bibliographische Detailangaben
Hauptverfasser:	MARTINEZ, ROGELIO, L, CHILDERS, WAYNE, E, ABOU-GHARBIA, MAGID, GHIDU, VICTOR, P
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to pharmaceutical compositions comprising furan-2-sulfonamide derivatives. The present invention further relates to methods of treatment of diseases or conditions associated with endothelial lipase activity, including coronary artery disease and low HDL-C. La présente invention concerne des compositions pharmaceutiques comprenant des dérivés de furane-2-sulfonamides. Elle concerne également des méthodes de traitement de maladies ou d'états associés à l'activité de la lipase endothéliale, y compris la coronaropathie et le faible taux de cholestérol HDL.