MICROCHIP STRUCTURE AND TREATMENTS FOR ELECTROCHEMICAL DETECTION

Disclosed herein are a process for the manufacture of a biosensing device, comprising the steps of providing a substrate having an electrically conductive lead on a surface thereof; applying an insulating layer to the surface and the lead, said insulating layer comprising one or more silicon dioxide...

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Bibliographische Detailangaben
Hauptverfasser: JACK, GRAHAM, D, HAYMAN, RYAN, B
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:Disclosed herein are a process for the manufacture of a biosensing device, comprising the steps of providing a substrate having an electrically conductive lead on a surface thereof; applying an insulating layer to the surface and the lead, said insulating layer comprising one or more silicon dioxide or silicon nitride; etching an aperture in the insulating layer to expose a portion of the lead onto which a nanostructured microelectrode is to be plated; oxidizing one or more of the silicon dioxide or silicon nitride to form oxidized silicon dioxide or silicon nitride; allowing one or more of the oxidized silicon dioxide or silicon nitride to react with a functionalized silane, for use in the electrochemical detection of a target on a sample. La présente invention concerne des procédés et des dispositifs destinés à être utilisés pour la détection électrochimique d'une cible dans un échantillon.