NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS

The present invention discloses compounds according to Formula (I), wherein R1, R2, R3, L, and the subscript m are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions, and methods o...

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Bibliographische Detailangaben
Hauptverfasser:	MENET, CHRISTEL, VAN DER PLAS, STEVEN, TRICARICO, GIOVANNI, MAMMOLITI, OSCAR, DE BLIECK, ANN, JOANESSE, CAROLINE, KELGTERMANS, HANS, DE MUNCK, TOM
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention discloses compounds according to Formula (I), wherein R1, R2, R3, L, and the subscript m are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions, and methods of treatment using the same, for the treatment of cystic fibrosis by administering a compound of the invention. La présente invention concerne des composés répondant à la formule (I), où R1, R2, R3, L et l'indice m sont tels que définis dans la description. La présente invention concerne des composés et leur utilisation dans le traitement de la mucoviscidose, leurs procédés de production, des compositions pharmaceutiques et des méthodes de traitement les utilisant, pour le traitement de la mucoviscidose par l'administration d'un composé de l'invention.