METHODS FOR PRODUCING ANTIBODIES

The present invention describes a method for producing an antibody in Pichia pastoris, such as by fed-batch fermentation. The method includes a respiratory quotient control for monitoring the ethanol profile and to improve the quality of the antibody by, for example, eliminating clipping of the heav...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CAMPBELL, GEORGE S, YOU, LI, XING, ZIZHUO, QIAN, YUEMING, EAGAN, BRUCE E, XU, XUANKUO, LI, ZHENGJIAN, QIAN, NAN-XIN
Format: Patent
Sprache:eng ; fre
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