POLYMORPHIC FORMS

The present invention relates to novel salt forms with improved manufacturability and solid-state properties of [6-Fluoro-1-(4-morpholin-4-ylmethyl-phenyl)-5,5-dioxo-4,5- dihydro-1 H-5l6-thiochromeno[4,3-c]pyrazol-3-yl]-morpholin-4-yl-methanone, and to methods of their manufacture. La présente inven...

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Hauptverfasser: DONINI, CRISTINA, VOISIN, FLORENT, MUZURELLE, MATHILDE, HARRIS, LUKE, KUEHN, CLEMENS, LEONARDI, ANDREA, MARIN, DELPHINE, GERBER, PATRICK, BECKER, AXEL, SAAL, CHRISTOPH, MEDERSKI, WERNER W. K. R
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to novel salt forms with improved manufacturability and solid-state properties of [6-Fluoro-1-(4-morpholin-4-ylmethyl-phenyl)-5,5-dioxo-4,5- dihydro-1 H-5l6-thiochromeno[4,3-c]pyrazol-3-yl]-morpholin-4-yl-methanone, and to methods of their manufacture. La présente invention concerne de nouvelles formes de sels présentant une manufacturabilité et des propriétés à l'état solide améliorées de [6-Fluoro-1-(4-morpholin-4-ylméthyl-phényl)-5,5-dioxo-4,5- dihydro-1 H-5l6-thiochroméno[4,3-c]pyrazol-3-yl]-morpholin-4-yl-méthanone, ainsi que des procédés pour leur fabrication.