FACTOR IXa INHIBITORS

The present invention provides a compound of Formula (I) wherein A is a heterocycle ring system and B is a heterocycle ring system or aryl ring system, and pharmaceutical compositions comprising one or more of said compounds, and methods for using said compounds for treating or preventing thromboses...

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Bibliographische Detailangaben
Hauptverfasser:	CHEN, YILI, HIRABAYASHI, TOMOKAZU, GREENLEE, WILLIAM JOHN, CHAN, TIN YAN, SHERER, EDWARD, CAMPEAU, LOUISARLES, CHEN, YI-HENG, LI, DERUN, SMITH, CAMERON JAMES, CHACKALAMANNIL, SAMUEL, KATSUNO, MIKA, GUO, LIANGQIN, TAN, JOHN QIANG, BALKOVEC, JAMES
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides a compound of Formula (I) wherein A is a heterocycle ring system and B is a heterocycle ring system or aryl ring system, and pharmaceutical compositions comprising one or more of said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. La présente invention concerne un composé de Formule (I) (I) où A est un système de cycle hétérocycle et B est un système de cycle hétérocycle ou un système de cycle aryle, et des compositions pharmaceutiques comprenant un ou plusieurs desdits composés, et des procédés d'utilisation desdits composés pour le traitement ou la prévention de thromboses, d'embolies, de l'hypercoagulabilité ou des modifications fibrotiques.