BLOOD-BRAIN BARRIER (BBB) PENETRATING DUAL SPECIFIC BINDING PROTEINS

Engineered multivalent and multispecific binding proteins capable of penetrating the blood-brain barrier (BBB) are provided, along with methods of making and uses in the prevention, diagnosis, and/or treatment of disease. L'invention concerne des protéines de liaison multivalentes et multi-spéc...

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Hauptverfasser:	HANZATIAN, DENISE, KARAOGLU, STERMAN, ANNETTE, J., SCHWARTZ, GHAYUR, TARIQ, GOODEARL, ANDREW, HARRIS, MARIA, CRISTINA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Engineered multivalent and multispecific binding proteins capable of penetrating the blood-brain barrier (BBB) are provided, along with methods of making and uses in the prevention, diagnosis, and/or treatment of disease. L'invention concerne des protéines de liaison multivalentes et multi-spécifiques génétiquement modifiées capables de pénétrer la barrière hémato-encéphalique (BBB), ainsi que des procédés de fabrication et des utilisations dans la prévention, le diagnostic et/ou le traitement d'une maladie.