CHEMICAL MODEL OF A NEURODEGENERATIVE DISEASE, METHOD FOR PREPARATION AND USES OF SAME

The invention concerns the use of pyridinium furosemide or one of the derivatives, analogues, salts, metabolites or prodrugs thereof in the preparation of a chemical model of a neurodegenerative disease, preferably Parkinson's disease. The invention also concerns the corresponding chemical mode...

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Bibliographische Detailangaben
Hauptverfasser:	MARTENS, THIERRY, LEHRI-BOUFALA, SONIA, MORIN, CHRISTOPHE, RIVARD, MICHAËL, LAURENCÉ, CÉLINE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Beschreibung
Zusammenfassung:	The invention concerns the use of pyridinium furosemide or one of the derivatives, analogues, salts, metabolites or prodrugs thereof in the preparation of a chemical model of a neurodegenerative disease, preferably Parkinson's disease. The invention also concerns the corresponding chemical model and the uses of same, in particular in screening tests for identifying drug candidates. L'invention a pour objet l'utilisation du pyridinium de furosémide ou de l'un de ses dérivés, analogues, sels, métabolites ou prodrogues dans la préparation d'un modèle chimique d'une maladie neurodégénérative, de préférence la maladie de Parkinson. L'invention a également pour objet le modèle chimique correspondant et ses utilisations, en particulier dans des tests de criblage pour l'identification de candidat-médicaments.