INDOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH INDOLES AND THEIR USE AS DNA METHYLATION MODULATORS

The present invention refers to compounds of formula (I): as well as to a method for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or chemoprevention of cancer hematological malignancy, proliferative diseases, genetic diseases, neurological...

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Hauptverfasser: OTAEGUI ANSA, DORLETA, ALDABA ARÉVALO, ENEKO, MASDEU MARGALEF, MARÍA DEL CARMEN, COSSÍO MORA, FERNANDO PEDRO, SAN SEBASTIÁN LARZABAL, EIDER, VILLAFRUELA CÁNEVA, SERGIO, VARA SALAZAR, YOSU ION, ALCALÁ CAFFARENA, MARÍA REMEDIOS, ZUBIA OLASCOAGA, AIZPEA
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention refers to compounds of formula (I): as well as to a method for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or chemoprevention of cancer hematological malignancy, proliferative diseases, genetic diseases, neurological disorders and immunological disorders. La présente invention concerne des composés de formule (I) : ainsi qu'un procédé pour leur préparation, des compositions pharmaceutiques comprenant ceux-ci, et leur utilisation pour le traitement et/ou la chimio-prévention d'une malignité hématologique cancéreuse, de maladies prolifératives, de maladies génétiques, de troubles neurologiques et de troubles immunologiques.