INSULIN-MIMETIC LOCAL THERAPEUTIC ADJUNCTS FOR ENHANCING SPINAL FUSION

Bone tissue materials comprising insulin-mimetic agents, such as suitable zinc, vanadium, tungsten, molybdenum, niobium, selenium, and manganese compounds, for facilitating spinal fusion of vertebrae in spinal fusion surgical procedures, and methods thereof. Additionally provided is a bone tissue ki...

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Bibliographische Detailangaben
Hauptverfasser:	VIVES, MICHAEL, J, LIN, SHELDON, SUTON, KOERNER, JOHN, BENEVENIA, JOSEPH, BREITBART, ERIC
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BANDAGES, DRESSINGS OR ABSORBENT PADS BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS ENZYMOLOGY FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS PROSTHESES SPIRITS TREATMENT OR PROTECTION OF EYES OR EARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Bone tissue materials comprising insulin-mimetic agents, such as suitable zinc, vanadium, tungsten, molybdenum, niobium, selenium, and manganese compounds, for facilitating spinal fusion of vertebrae in spinal fusion surgical procedures, and methods thereof. Additionally provided is a bone tissue kit for facilitating fusion of vertebrae in a spinal fusion surgical procedure including a composition formulated for facile application in a spinal fusion procedure comprising an insulin-mimetic agent and a pharmaceutically acceptable carrier. Yet further provided is an implantable device for enhancing spinal fusion including a prosthetic implant configured to stabilize and promote the fusion of two adjacent vertebrae, wherein the bone tissue contacting surfaces of the prosthetic implant are coated with a composition comprising an insulin-mimetic agent. L'invention concerne des matières de tissu osseux, comprenant des agents insulinomimétiques, tels que des composés appropriés de zinc, de vanadium, de tungstène, de molybdène, de niobium, de sélénium et de manganèse, pour faciliter une fusion vertébrale de vertèbres lors d'interventions chirurgicales de fusion vertébrale, et leurs procédés. L'invention concerne également un coffret de tissu osseux pour faciliter une fusion de vertèbres lors d'une intervention chirurgicale de fusion vertébrale, comprenant une composition formulée pour une application facile lors d'une intervention de fusion vertébrale comprenant un agent insulinomimétique et un support pharmaceutiquement acceptable. L'invention concerne en outre un dispositif implantable pour favoriser une fusion vertébrale, comprenant un implant prothétique configuré pour stabiliser et favoriser la fusion de deux vertèbres adjacentes, les surfaces de contact de tissu osseux de l'implant prothétique étant revêtues d'une composition comprenant un agent insulinomimétique.