STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS

Provided herein are stapled or stitched polypeptides comprising an alpha-helical segment, wherein the polypeptide binds to the insulin receptor, and wherein the polypeptide comprises at least two cross-linked amino acids as shown in Formula (iii), or at least three cross-linked amino acids as shown...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	ZHOU, MINYUN, LIANG, REBECCA, YUE, VERDINE, GREGORY, L
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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