AZAQUINAZOLINE INHIBITORS OF ATYPICAL PROTEIN KINASE C

The present invention provides a compound of formula (I) or a salt thereof, wherein R7, R8, R9, G, and X are as defined herein. A compound of formula (I) and its salts have a PKC inhibitory activity, and may be used to treat proliferative disorders. La présente invention concerne un composé de formu...

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Hauptverfasser:	MONCK, NATHANIEL, JT, HUDKINS, ROBERT, L, OTT, GREGORY, R, ZIFICSAK, CRAIG, A, BRESLIN, HENRY, J, DORSEY, BRUCE, D, MORRIS, EMMA, L, MESAROS, EUGEN, F, ZULLI, ALLISON, L, SOUDY, CHRISTELLE, N, PAVE, GREGOIRE, A, DUGAN, BENJAMIN, J, FOWLER, KATHERINE, M, ROFFEY, JONATHAN, R. A, TAO, MING, OLOWOYE, IKEOLUWA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a compound of formula (I) or a salt thereof, wherein R7, R8, R9, G, and X are as defined herein. A compound of formula (I) and its salts have a PKC inhibitory activity, and may be used to treat proliferative disorders. La présente invention concerne un composé de formule (I) ou un sel correspondant, R7, R8, R9, G et X étant tels que définis dans la description. Un composé de formule (I) et ses sels présentent une activité d'inhibition de PKC et peuvent être utilisés pour le traitement de troubles prolifératifs.