PROCESS FOR THE PREPARATION OF DABIGATRAN ETEXILATE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

The present invention relates to a process for the preparation of dabigatran etexilate. The present invention also relates to trifluoroacetate salt of dabigatran etexilate and a process for its preparation. The present invention further relates to crystalline Form I and crystalline Form II of triflu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	SANWAL, SUDHIR SINGH, THAPER, RAJESH KUMAR, MURUGESAN, BALAGURU, VEMPALI, ANANDAM, PRASAD, MOHAN, SATHYANARAYANA, SWARGAM
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to a process for the preparation of dabigatran etexilate. The present invention also relates to trifluoroacetate salt of dabigatran etexilate and a process for its preparation. The present invention further relates to crystalline Form I and crystalline Form II of trifluoroacetate salt of dabigatran etexilate and processes for their preparation. The present invention further relates to a process for the preparation of pharmaceutically acceptable salts, including methanesulfonate salt, of dabigatran etexilate. La présente invention concerne un procédé de préparation d'étéxilate de dabigatran. La présente invention concerne également le sel trifluoroacétate d'étéxilate de dabigatran et son procédé de préparation. Elle concerne en outre la forme cristalline I et la forme cristalline II du sel trifluoroacétate d'étéxilate de dabigatran et leurs procédés de préparation. Elle concerne enfin un procédé de préparation de sels pharmaceutiquement acceptables, dont le sel méthanesulfonate de l'étéxilate de dabigatran.