SYNTHETIC PNTX(19) PEPTIDE, PHARMACEUTICAL COMPOSITIONS AND USE

The present invention relates to a synthetic peptide having 19 amino acids, called PnTx(19), formed from the sequence of the native PnTx2-6 toxin from the Phoneutria nigriventer spider. The invention also relates to pharmaceutical compositions containing this peptide and to the use thereof for the t...

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Hauptverfasser: DA SILVA LOMEO, ROSANGELA, LACERDA BEIRAO, PAULO SERGIO, MONTEIRO DE CASTRO PIMENTA, ADRIANO, NUNES DA SILVA, CAROLINA, SILVA TORRES, FERNANDA, DE LIMA PEREZ GARCIA, MARIA ELENA, DE MARCO ALMEIDA, FLAVIA
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creator DA SILVA LOMEO, ROSANGELA
LACERDA BEIRAO, PAULO SERGIO
MONTEIRO DE CASTRO PIMENTA, ADRIANO
NUNES DA SILVA, CAROLINA
SILVA TORRES, FERNANDA
DE LIMA PEREZ GARCIA, MARIA ELENA
DE MARCO ALMEIDA, FLAVIA
description The present invention relates to a synthetic peptide having 19 amino acids, called PnTx(19), formed from the sequence of the native PnTx2-6 toxin from the Phoneutria nigriventer spider. The invention also relates to pharmaceutical compositions containing this peptide and to the use thereof for the treatment of erectile dysfunction and/or for enhancing erectile function. La présente invention concerne un peptide synthétique de 19 acides aminés, appelé PnTx(19), construit à partir de la séquence de la toxine native PnTx2-6, de l'araignée Phoneutria nigriventer. Elle concerne en outre des compositions pharmaceutiques contenant ce peptide ainsi que leur utilisation dans le traitement de la dysfonction érectile et/ou dans la potentialisation de la fonction érectile. A presente invenção refere-se a um peptídeo sintético de 19 aminoácidos, denominado PnTx(19), construído a partir da sequência da toxina nativa PnTx2-6, da aranha Phoneutria nigriventer. Refere-se também a composições farmacêuticas contendo tal peptídeo e ao seu uso no tratamento da disfunção erétil e/ou na potencialização da função erétil.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SYNTHETIC PNTX(19) PEPTIDE, PHARMACEUTICAL COMPOSITIONS AND USE
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