COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR PLAQUE SOFTENING

Disclosed herein is a compound for use in a composition applied to a blood vessel, wherein the compound softens and/or disrupts the crystalline matrix of calcified plaque. Methods of treatment comprising applying the disclosed composition are also disclosed. Plaque-softening compounds are also discl...

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Hauptverfasser: ELBERT, JEFFREY E, UTECHT, RONALD E, HABERER, BARBARA R, DOWNEY, THERESE J
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creator ELBERT, JEFFREY E
UTECHT, RONALD E
HABERER, BARBARA R
DOWNEY, THERESE J
description Disclosed herein is a compound for use in a composition applied to a blood vessel, wherein the compound softens and/or disrupts the crystalline matrix of calcified plaque. Methods of treatment comprising applying the disclosed composition are also disclosed. Plaque-softening compounds are also disclosed. Cette invention concerne un composé utilisé dans une composition appliquée sur un vaisseau sanguin, ledit composé ramollissant et/ou perturbant la matrice cristalline de la plaque calcifiée. L'invention concerne également des méthodes de traitement consistant à appliquer ladite composition. L'invention concerne par ailleurs les composés utilisés pour ramollir les plaques calcifiées.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR PLAQUE SOFTENING
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