COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR PLAQUE SOFTENING

Disclosed herein is a compound for use in a composition applied to a blood vessel, wherein the compound softens and/or disrupts the crystalline matrix of calcified plaque. Methods of treatment comprising applying the disclosed composition are also disclosed. Plaque-softening compounds are also discl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	ELBERT, JEFFREY E, UTECHT, RONALD E, HABERER, BARBARA R, DOWNEY, THERESE J
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Disclosed herein is a compound for use in a composition applied to a blood vessel, wherein the compound softens and/or disrupts the crystalline matrix of calcified plaque. Methods of treatment comprising applying the disclosed composition are also disclosed. Plaque-softening compounds are also disclosed. Cette invention concerne un composé utilisé dans une composition appliquée sur un vaisseau sanguin, ledit composé ramollissant et/ou perturbant la matrice cristalline de la plaque calcifiée. L'invention concerne également des méthodes de traitement consistant à appliquer ladite composition. L'invention concerne par ailleurs les composés utilisés pour ramollir les plaques calcifiées.