PROCESS FOR MANUFACTURING A PHARMACEUTICAL DOSAGE FORM COMPRISING NIFEDIPINE AND CANDESARTAN CILEXETIL

The present invention relates to manufacturing processes for the preparation of a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil and optionally at least one diuretic characterized in that nifedipine is released in the body in a controlled (modified) manner and the candesa...

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Bibliographische Detailangaben
Hauptverfasser:	KNOP, KLAUS, JUST, SARAH, MEENERS, ANDREAS, MEYER, GUENTER, FUNKE, ADRIAN, SMIKALLA, MARTINA, WIRGES, MARKUS, ZEITLER, JOCHEN, AXEL, KLEINEBUDDE, PETER, BROCK, DANIELA, BOEGGERING, ROLF-ANTON
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BABY COMFORTERS CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY DEVICES FOR RECEIVING SPITTLE DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to manufacturing processes for the preparation of a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil and optionally at least one diuretic characterized in that nifedipine is released in the body in a controlled (modified) manner and the candesartan cilexetil is released rapidly (immediate release (IR)) and optionally the diuretic is released rapidly (immediate release (IR)) and the pharmaceutical dosage forms obtainable by these processes. La présente invention concerne des procédés de fabrication pour la préparation d'une forme pharmaceutique comprenant de la nifédipine et du candésartan cilexétil et facultativement au moins un diurétique, caractérisé en ce que la nifédipine est libérée dans le corps d'une manière contrôlée (modifiée) et le candésartan cilexétil est libéré rapidement (libération immédiate (IR)) et facultativement le diurétique est libéré rapidement (libération immédiate (IR)), et les formes pharmaceutiques pouvant être obtenues par ces procédés.