1-(DIHYDRONAPHTHALENYL)PYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS

This invention relates to novel 1-(dihydronaphthalenyl)pyridones which are antagonists of the melanin-concentrating hormone receptor 1 (MCHR1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of obesity and diabetes. L...

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Bibliographische Detailangaben
Hauptverfasser:	YUAN, JIANGXING, LV, MAOYUN, YU, HAIYU, XU, SHANLI, YAO, CHEN, GAO, MIN, QIN, DONGHUI, WU, CHENGDE, HUANG, XING, CHRISTENSEN, IV, SIEGFRIED BENJAMIN, LIN, XIAOJUAN, LI, LEI, ZHANG, ZHILIU
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to novel 1-(dihydronaphthalenyl)pyridones which are antagonists of the melanin-concentrating hormone receptor 1 (MCHR1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of obesity and diabetes. L'invention concerne de nouvelles 1-(dihydronaphtalényl)pyridones qui sont des antagonistes du récepteur 1 de l'hormone de concentration de la mélanine (MCHR1), des compositions pharmaceutiques les contenant, leurs procédés de préparation et leur utilisation en thérapie pour le traitement de l'obésité et du diabète.