1-(DIHYDRONAPHTHALENYL)PYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS

Provided are 1-(dihydronaphthalenyl)pyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy for the treatment of obesity and diabetes. L'invention concerne des...

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Hauptverfasser:	QIN, DONGHUI, WU, CHENGDE, YUAN, JIANGXING, CHRISTENSEN, SIEG, YU, HAIYU, ZHANG, ZHILIU
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Provided are 1-(dihydronaphthalenyl)pyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy for the treatment of obesity and diabetes. L'invention concerne des 1-(dihydronaphtalényl)pyridones qui sont des antagonistes du récepteur 1 de l'hormone de concentration de la mélanine (MCHR1), des compositions pharmaceutiques les contenant, des procédés pour leur préparation et leur utilisation dans une thérapie pour le traitement de l'obésité et du diabète.