GLYCEROL SOLVATE FORMS OF (R) - 2 - [ [ [3 -METHYL -4 (2,2, 2 - TRIFLUOROETHOXY) PYRIDIN- 2 - YL] METHYL] SULPHINYL] - 1H - BEN ZIMIDAZOLE

GLYCEROL SOLVATE FORMS OF (R) - 2 - [ [ [3 -METHYL -4 (2,2, 2 - TRIFLUOROETHOXY) PYRIDIN- 2 - YL] METHYL] SULPHINYL] - 1H - BEN ZIMIDAZOLE

The present invention relates to novel crystalline forms of (R)-2-[[[3-methyl-4(2,2,2- trifluoroethoxy)pyridin-2-yl]methyl]sulphinyl]-lH-benzimidazole (Formula 1), to processes for their preparation, to pharmaceutical compositions comprising the same and to the use of such crystalline forms for the...

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Hauptverfasser: SRINIVAS, PATHI L, MALHOTRA, GEENA, RAMASUBBU, CHANDRASEKARAN, KANATHALA, SHASHI REKHA, RAO, DHARMARAJ RAMACHANDRA, GANGRADE, MANISH, JAYACHANDRAN, JENNET, PURANDARE, SHRINIVAS MADHUKAR, KANKAN, RAJENDRA NARAYANRAO
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present invention relates to novel crystalline forms of (R)-2-[[[3-methyl-4(2,2,2- trifluoroethoxy)pyridin-2-yl]methyl]sulphinyl]-lH-benzimidazole (Formula 1), to processes for their preparation, to pharmaceutical compositions comprising the same and to the use of such crystalline forms for the treatment of gastrointestinal (GI) disorders. La présente invention concerne des nouvelles formes cristallines de (R)-2-[[[3-methyl-4(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]sulphinyl]-lH-benzimidazole (Formule 1), des procédés pour leur préparation, des compositions pharmaceutiques les comprenant et l'utilisation de telles formes cristallines pour le traitement de troubles gastro-intestinaux (GI).