USE OF RBM39 AS A BIOMARKER

The present invention relates to the use (i) of a level of expression of a long RBM39 protein isoform, termed RBM39L, and (ii) of a level of expression of a short RBM39 protein isoform, termed RBM39C, as a marker for the efficacy of an active agent capable of preventing and/or treating HIV infection...

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Bibliographische Detailangaben
Hauptverfasser:	GARCEL, AUDE, MAHUTEAU-BETZER, FLORENCE, TAZI, JAMAL, SCHERRER, DIDIER, CAMPOS, NOELIE, NAJMAN, ROMAIN, VENABLES, JULIAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to the use (i) of a level of expression of a long RBM39 protein isoform, termed RBM39L, and (ii) of a level of expression of a short RBM39 protein isoform, termed RBM39C, as a marker for the efficacy of an active agent capable of preventing and/or treating HIV infection. La présente invention concerne l'utilisation (i) d'un taux d'expression d'une isoforme longue d'une protéine RBM39, dite RBM39L, et (ii) d'un taux d'expression d'une isoforme courte d'une protéine RBM39, dite RBM39C, comme marqueur de l'efficacité d'un actif apte à prévenir et/ou traiter une infection à VIH.