RECOMBINANT TRIVALENT VACCINE AGAINST HUMAN INFLUENZA

The invention relates to the field of medicine. The recombinant trivalent vaccine against human influenza comprises a recombinant adenoviral vector with a nucleotide sequence coding for at least one antigen of the influenza virus strain, and also an immunostimulator and a formulating buffer. Three t...

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Bibliographische Detailangaben
Hauptverfasser:	PICHUGIN, ALEKSEY VASILIEVICH, ATAULLAKHANOV, RAVSHAN INOYATOVICH, KHAITOV, RAKHIM MUSAEVICH, SHMAROV, MAKSIM MIKHAILOVICH, ATAULLAKHANOV, RUSTAM RAVSHANOVICH, SEDOVA, ELENA SERGEEVNA, LOGUNOV, DENIS JURIEVICH
Format:	Patent
Sprache:	eng ; fre ; rus
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to the field of medicine. The recombinant trivalent vaccine against human influenza comprises a recombinant adenoviral vector with a nucleotide sequence coding for at least one antigen of the influenza virus strain, and also an immunostimulator and a formulating buffer. Three types of non-replicating nanoparticles on the basis of a genome of human adenovirus of serotype 5 capable of expressing haemagglutinins of the influenza virus are used as the adenoviral vector. L'invention se rapporte au domaine de la médecine et concerne un vaccin recombinant trivalent contre la grippe humaine, lequel comprend un vecteur d'adénovirus recombinant avec une séquence nucléotidique codant au moins un anticorps de la souche du virus de la grippe, ainsi qu'un immunostimulant et un tampon de formulation. Le vecteur d'adénovirus consiste en trois types de nanoparticules non répliquantes à base de génome d'adénovirus humain de sérotype 5, lesquelles permettent d'exprimer les hémagglutinines du virus de la grippe.