PROCESS OF MODULATING MAN5 AND/OR AFUCOSYLATION CONTENT OF GLYCOPROTEIN COMPOSITION

Provided is a method for producing glycoprotein composition with an increased percentage of Man5 and/or afucosylated glycans. Use of manganese for increasing the percentage of Man5 and afucosylated glycans in glycoprotein composition is further provided. L'invention concerne un procédé de produ...

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Hauptverfasser:	BHAVSAR, KAUMIL, GARG, NEHA, MADHAVA RAM, PARANANDI ANANTA, THUDUPPATHY, GURUVASUTHEVAN RAMASAMY
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided is a method for producing glycoprotein composition with an increased percentage of Man5 and/or afucosylated glycans. Use of manganese for increasing the percentage of Man5 and afucosylated glycans in glycoprotein composition is further provided. L'invention concerne un procédé de production d'une composition de glycoprotéine ayant un pourcentage augmenté de Man5 et/ou de glycanes afucosylés. Elle concerne également l'utilisation de manganèse pour augmenter le pourcentage de Man5 et de glycanes afucosylés dans une composition de glycoprotéine.