ANTI-CRAC CHANNEL ANTIBODIES

The invention relates to antibodies that specifically bind to calcium release- activated calcium (CRAC) channels and inhibit the influx of calcium through CRAC channels. Such antibodies can modulate T cell activation and function. L'invention concerne des anticorps qui se lient spécifiquement à...

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Bibliographische Detailangaben
Hauptverfasser:	ZAHN, STEFAN, ODEGARD, VALERIE, PADKJAER, SOEREN, BERG
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to antibodies that specifically bind to calcium release- activated calcium (CRAC) channels and inhibit the influx of calcium through CRAC channels. Such antibodies can modulate T cell activation and function. L'invention concerne des anticorps qui se lient spécifiquement à des canaux calciques dépendants de la libération de calcium (CRAC) et inhibent l'influx de calcium à travers les canaux CRAC. De tels anticorps peuvent moduler l'activation et la fonction de lymphocytes T.