MICROORGANISMS AND METHODS FOR PRODUCING ACRYLATE AND OTHER PRODUCTS FROM HOMOSERINE

This invention relates to microorganisms that convert a carbon source to acrylate or other desirable products using homoserine and 2-keto-4-hydroxybutyrate as intermediates. The invention provides genetically engineered microorganisms that carry out the conversion, as well as methods for producing a...

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Bibliographische Detailangaben
Hauptverfasser:	VELASQUEZ, JUAN, ESTEBAN, GREEN, PHILLIP, RICHARD, XU, JUN, SAUNDERS, CHARLES, WINSTON
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMES ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	This invention relates to microorganisms that convert a carbon source to acrylate or other desirable products using homoserine and 2-keto-4-hydroxybutyrate as intermediates. The invention provides genetically engineered microorganisms that carry out the conversion, as well as methods for producing acrylate by culturing the microorganisms. Also provided are microorganisms and methods for converting homoserine to 3-hydroxypropionyl-CoA, 3-hydroxypropionate (3HP), poly-3-hydroxypropionate and 1,3-propanediol. Cette invention concerne des microorganismes qui convertissent une source de carbone en acrylate ou autres produits souhaitables à l'aide d'homosérine et de 2-céto-4-hydroxybutyrate comme intermédiaires. L'invention porte sur des microorganismes génétiquement modifiés qui effectuent la conversion, ainsi que sur des procédés de production d'acrylate par culture des microorganismes. L'invention concerne également des microorganismes et des procédés de conversion d'homosérine en 3-hydroxypropionyl-CoA, 3-hydroxypropionate (3HP), poly-3-hydroxypropionate et 1,3-propanediol.