PYRAZOLO[4,3-C]PYRIDINE DERIVATIVES AS KINASE INHIBITORS

The present invention relates to compounds of formula (I) wherein X1 to X5, Y, ZA, ZB, R and A have the meaning as cited in the description and the claims. Said compounds are useful as kinase inhibitors for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders,...

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Bibliographische Detailangaben
Hauptverfasser:	RAMSDEN, NIGEL, DAGOSTIN, CLAUDIO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to compounds of formula (I) wherein X1 to X5, Y, ZA, ZB, R and A have the meaning as cited in the description and the claims. Said compounds are useful as kinase inhibitors for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically- mediated diseases. The invention also relates to pharmaceutical compositions including said compounds as well as the use as medicaments. La présente invention concerne des composés de formule (I) dans laquelle X1 à X5, Y, ZA, ZB, R et A ont la signification donnée dans la description et les revendications. Lesdits composés sont utiles comme inhibiteurs de kinases pour le traitement ou la prophylaxie de troubles immunologiques, inflammatoires, auto-immuns et allergiques, et de maladies à médiation immunologique. L'invention concerne également des compositions pharmaceutiques comprenant lesdits composés ainsi que leur utilisation comme médicaments.