DENGUE-VIRUS SEROTYPE NEUTRALIZING ANTIBODIES

Materials and methods are provided for treating dengue infections. Human monoclonal antibodies against all serotypes of dengue virus are also provided. Methods of using human monoclonal antibodies to neutralize all dengue-virus serotypes are provided using patients' peripheral blood lymphocytes...

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Hauptverfasser:	ANANTAPREECHA, SURAPEE, PRACHASUPHAP, APICHAI, SAWANPANYALERT, PATHOM, THATTIYAPHONG, AREE, KUHARA, MOTOKI, DHEPAKSON, PANADDA, SETTHAPRAMOTE, CHAYANEE, IKUTA, KAZUYOSHI, RAMASOOTA, PONGRAMA, A-NUEGOONPIPAT, ATCHAREEYA, SASAKI, TADAHIRO, OKUNO, YOSHINOBU
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	Materials and methods are provided for treating dengue infections. Human monoclonal antibodies against all serotypes of dengue virus are also provided. Methods of using human monoclonal antibodies to neutralize all dengue-virus serotypes are provided using patients' peripheral blood lymphocytes. La présente invention concerne des matériaux et des méthodes permettant de traiter les infections par le virus de la dengue. L'invention concerne également des anticorps monoclonaux humains dirigés contre 11 sérotypes du virus de la dengue. L'invention concerne, par ailleurs, des méthodes consistant à utiliser des anticorps monoclonaux humains afin de neutraliser tous les sérotypes du virus de la dengue, lesdites méthodes faisant appel aux lymphocytes du sang périphérique des patients.