NOVEL INTERMEDIATE USED FOR PREPARING TAPENTADOL OR ANALOGUES THEREOF

Disclosed is a novel intermediate used for preparing tapentadol and their analogues, wherein the structure of the intermediate is expressed by formula I or II, and the groups are defined as the description. Also disclosed are the process for preparing the novel intermediate and its use for preparing tapentadol or its analogues. The yield and quality of tapentadol product may be increased obviously, while the cost of production is reduced, and the step of production is simplified. The synthesizing process is environment-friendly, and it is adapt much more to the request of industrialization production. La présente invention concerne un nouvel intermédiaire utilisé pour préparer du tapentadol et ses analogues, la structure de l'intermédiaire étant exprimée par la formule I ou II, et les groupes étant définis dans la description. L'invention concerne également le procédé de préparation du nouvel intermédiaire et son utilisation pour la préparation de tapentadol ou ses analogues. Le rendement et la qualité du tap