RECOMBINANT APOA-1M FROM ENGINEERED BACTERIA

Apolipoprotein A-1 Milano (ApoA-1M), the protein component of a high-density lipoprotein (HDL) mimic with promising potential for reduction of atherosclerotic plaque, is produced on a large scale by expression in E. coli. Significant difficulty with clearance of host cell proteins (HCPs) was experie...

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Hauptverfasser:	WANG, XING, HUNTER, ALAN, K, BISHOP, BRUCE, F, CAPARON, MARIE, H, HO, SA, V, MCLAUGHLIN, JOSEPH, K, THOMAS, KRISTEN, E, LANTER, PAUL, B, DUFIELD, ROBERT, L, RUST, KEVIN, J, HERBERG, JOHN, T, SHELL, ROBERT, E
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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