5HT1A ANTAGONIST USEFUL FOR IN VIVO IMAGING

The present invention provides a novel compound of formula (I) useful for in vivo imaging of 5-HT1 A receptors in a subject. Also provided by the present invention is a precursor compound useful in the preparation of the compound of the invention, as well as said method of preparation. The present i...

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Bibliographische Detailangaben
1. Verfasser:	NEWINGTON, IAN, MARTIN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a novel compound of formula (I) useful for in vivo imaging of 5-HT1 A receptors in a subject. Also provided by the present invention is a precursor compound useful in the preparation of the compound of the invention, as well as said method of preparation. The present invention additionally provides methods for the use of the compound of the invention in an in vivo imaging method, and use of that in vivo imaging method in diagnosis and therapy monitoring. La présente invention concerne un nouveau composé de formule (I) utile pour l'imagerie in vivo de récepteurs 5-HT1A chez un sujet. La présente invention concerne également un composé précurseur utile dans la préparation du composé de l'invention, ainsi que ledit procédé de préparation. La présente invention concerne en outre des procédés pour l'utilisation du composé de l'invention dans un procédé d'imagerie in vivo et l'utilisation de ce procédé d'imagerie in vivo dans le diagnostic et la surveillance de la thérapie.