AGR2 BLOCKING ANTIBODY AND USE THEREOF

Disclosed is an AGR2 blocking monoclonal antibody, and in particular, a humanized monoclonal antibody for blocking AGR2. Also disclosed is a pharmaceutical composition containing the antibody and a method for preparing the same, and a use of the antibody in blocking tumor growth and metastasis. L�...

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Bibliographische Detailangaben
Hauptverfasser: WU, ZHENGHUA, ZHU, QI, GUO, HAO, MASHAUSI, DHAHIRI S, LI, DAWEI
Format: Patent
Sprache:chi ; eng ; fre
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Zusammenfassung:Disclosed is an AGR2 blocking monoclonal antibody, and in particular, a humanized monoclonal antibody for blocking AGR2. Also disclosed is a pharmaceutical composition containing the antibody and a method for preparing the same, and a use of the antibody in blocking tumor growth and metastasis. L'invention concerne un anticorps monoclonal bloquant d'AGR2 et, en particulier, un anticorps monoclonal humanisé pour le blocage d'AGR2. L'invention concerne également une composition pharmaceutique contenant l'anticorps et un procédé de préparation de celui-ci, et une utilisation de l'anticorps dans le blocage de la croissance tumorale et de la métastase tumorale.