GLYCINE B ANTAGONISTS

The invention relates to 2(1H)-quinolinone derivatives of formula (I) as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are glycine B antagonists and are therefore useful for the contro...

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Bibliographische Detailangaben
Hauptverfasser: PISKUNOVA, IRENA, WOLTER, FALKO ERNST, KRUEGER, BJOERN, SEMENIHINA, VALENTINA, ROZHKOVS, JEVGENIJS, KAUSS, VALERJANS, HANSEN, ANGELA, PELSS, JURIS, ABEL, ULRICH
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to 2(1H)-quinolinone derivatives of formula (I) as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are glycine B antagonists and are therefore useful for the control and prevention of various disorders, including neurological disorders. L'invention concerne des dérivés de la 2(1H)-quinolinone représentés par la formule (I), ainsi que les sels pharmaceutiquement acceptables de ceux-ci. L'invention concerne de plus un procédé de préparation de tels composés. Les composés de l'invention constituent des antagonistes de la glycine B, et sont par conséquent utiles pour réguler et prévenir divers troubles, y compris des troubles neurologiques.