NOVEL CRYSTALLINE SALTS OF ASENAPINE WITH ORGANIC DI-ACIDS AND TRI-ACIDS
The invention relates to novel crystalline salts of Asenapine (I) with organic di-acids and tri-acids and to methods of their preparation. Furthermore the invention relates to the use of the novel salts in pharmaceutical compositions and to the use of the novel salts as medicaments, preferably in th...
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Zusammenfassung: | The invention relates to novel crystalline salts of Asenapine (I) with organic di-acids and tri-acids and to methods of their preparation. Furthermore the invention relates to the use of the novel salts in pharmaceutical compositions and to the use of the novel salts as medicaments, preferably in the treatment of psychotic diseases or disorders such as schizophrenia and acute mania associated with bipolar disorder.
L'invention concerne de nouveaux sels cristallins d'asénapine (I) contenant des diacides et triacides organiques et leurs procédés de préparation. L'invention concerne en outre l'utilisation de ces nouveaux sels dans des compositions pharmaceutiques et l'utilisation de ces nouveaux sels comme médicaments, de préférence dans le traitement de maladies ou de troubles psychotiques tels que la schizophrénie et la manie aiguë associée à un trouble bipolaire. |
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