PRODUCTION OF HETEROLOGOUS EXTRACELLULAR POLYPEPTIDES IN YARROWIA LIPOLYTICA

This invention relates to protein and/or polypeptide production, particularly improved production of extracellular heterologous polypeptides and proteins. In particular, the invention relates to compositions of cell populations capable of improved levels of extracellular secretion relative to contro...

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Hauptverfasser:	VAN ZYL, PETRUS JAKOBUS, RAMAGOMA, FARANANI, NTHANGENI, MULALO BETHUEL
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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creator	VAN ZYL, PETRUS JAKOBUS RAMAGOMA, FARANANI NTHANGENI, MULALO BETHUEL
description	This invention relates to protein and/or polypeptide production, particularly improved production of extracellular heterologous polypeptides and proteins. In particular, the invention relates to compositions of cell populations capable of improved levels of extracellular secretion relative to control populations, kits containing such compositions, methods of producing heterologous proteins of interest and recombinant microorganisms capable of improved extracellular heterologous protein production. Cette invention concerne la production de protéines et/ou de polypeptides, en particulier la production améliorée de polypeptides et de protéines hétérologues extracellulaires. En particulier, l'invention concerne des compositions de populations cellulaires aptes aux niveaux améliorés de sécrétion extracellulaire par rapport à des populations témoins, des trousses contenant de telles compositions, des procédés de fabrication de protéines hétérologues d'intérêt et des microorganismes recombinants aptes à une production améliorée de protéines hétérologues extracellulaires.
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subjects	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
title	PRODUCTION OF HETEROLOGOUS EXTRACELLULAR POLYPEPTIDES IN YARROWIA LIPOLYTICA
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