FLUOROPHENYL BICYCLIC HETEROARYL COMPOUNDS

The present invention provides a compound of formula (I); a method for manufacturing the compounds of the invention, and its use as a IGF-1R inhibitor. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. La présente invention conc...

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Bibliographische Detailangaben
Hauptverfasser:	CHEN, BAI, MARSILJE III, THOMAS H, FAIRHURST, ROBIN ALEC, LU, WENSHUO, MCCARTHY, CLIVE, STUTZ, STEFAN, MICHELLYS, PIERRE-YVES, JIANG, SONGCHUN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a compound of formula (I); a method for manufacturing the compounds of the invention, and its use as a IGF-1R inhibitor. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. La présente invention concerne un composé de formule (I); (I) un procédé de fabrication des composés selon l'invention, et leur utilisation comme inhibiteurs de IGF-1R. La présente invention concerne en outre une combinaison de principes actifs pharmacologiques et une composition pharmaceutique.